Well fantasy to Todd Howard is a knight riding around on a horse and killing things. His words.
About the Mage Guild. It doesn't matter if you're a vampire. You know that part where the old archmage suddenly keels over for no apparent reason after making you archmage? Well that's because he for some reason decided that the only way to defeat that pansy ass Altmer King of Worms bastardization was to entrap his soul in the soul crystal you'd given him, which would protect you from Mannimarco's powers of paralysis. Being a vampire has nothing to do with it, though I'm not in the least bit surprised that they didn't take that possibility into account.
Speaking of Altmer... What the crap was with the Altmer villains in this game? They made the King of Worms, a some super lich necromancer, into a fairly weak Altmer mage. And even more weird, they made the big bad of the game, the son of two Bosmer, an Altmer as well.
And speaking of the mage's guild, am I the only one that felt like the whole premise behind it was completely idiotic? I mean, basically the only reason you're fighting the necromancers is because the new archmage suddenly decided to ban necromancy for no apparent reason and hunt down all it's practitioners. Then when it turns out they're a bit tougher to massacre than he'd hoped you come along, his guardian angel of death. Yay, you saved us from the oppressed minority's attempts to continue existing! A hero is you! Also here's a chest that gets filled with fairly useless crap on an irregular basis.