So uhh... took a long break from Xcom 2 after my Dale Gribble got blown away in my campaign like a year ago (Truly one of the great voice packs, especially for a grenader).
Finally got in the groove with a new classic Ironman, doing pretty well, only like 4 deaths. Pretty much to end game (well, at 4 days Plasma and just had to start skulljacking/shadow chamber/all that jazz). Then I lose my best ranger to not being to pick him up while unconcious. Also 3 others killed (Dale Gribble, again!) because I gave it another turn and tried to pick him up from a different tile. Whatever, I decide to press on, very annoyed but determined. Cue next mission, fighting long odds on a wood map when I trigger 2 pods at once. Throw a mimic beacon and prepare for the pain, as there's 2 mutons, a heavy lancer, a sectoid and an advanced trooper. Mimic Beacon takes enough damage that I'll at least be able to grenade away cover and maybe get some good rolls so that everything won't go entirely pear shaped. Was totally willing to take a death or two.
Then grenades stop working. Acid grenade throws some acid around, frag grenade puts up some flaming scenery. The muton stands unimpressed, continuing to suppress my sniper. Not a misclick or anything, as if it had been one over it would've hit the lancer. Instant ragequit.
I'm definitely never playing ironman again.