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[Trekkin]

My prison is just my overflow hospital with sleeping spots between the beds, since I use the recruitment period to install all the relevant bionics for their eventual role. I've been meaning to try dosing them with yayo as well for the mood buff.

EDIT: Actually, has anyone tried making a drug-based colony? I mean making flake/yayo the primary source of positive moods.

[Yoink]

"Primary"? It usually ends up the only such source in my colonies.
Yeah, I'm not great at this game. Actually I haven't played in quite a while, been thinking about firing it up again.   

[Broseph Stalin]

My prison is just my overflow hospital with sleeping spots between the beds, since I use the recruitment period to install all the relevant bionics for their eventual role. I've been meaning to try dosing them with yayo as well for the mood buff.

EDIT: Actually, has anyone tried making a drug-based colony? I mean making flake/yayo the primary source of positive moods.

Oh totally. I mean you eat through pawns with the whole brain damage thing but it's very doable.

[Trekkin]

That was why I was thinking of flake and yayo specifically, since they only damage replaceable organs. I suspect tolerance would make the drug intake unprofitable to sustain at some point, though.

[Broseph Stalin]

I play modded so I don't know what's normal but "chemical damage" always takes out the brain for me.

[Culise]

Interesting.  In vanilla, it should vary based on the drug: the two hard cocaine drugs attack the kidneys (chemical damage), smokeleaf the lungs (asthma and/or carcinoma), and go-juice and wake-up the brain (chemical damage).  Beer can cause both liver (cirrhosis and/or carcinoma) and brain (chemical damage) damage.  Psychoid pekoe doesn't have such an effect to my knowledge, though that may be more due to its low addictiveness making it difficult to build up a tolerance on it alone.  Luciferium also doesn't do this, but its withdrawal effects are to die for.

I haven't mucked about lately with vanilla or drugs lately, though, so it's partially outdated experience and partially the wiki.

[Yoink]

Huh, I coulda sworn I remembered colonists getting all sorts of nasty brain stuff from flake and yayo? It seemed kinda like something that came in one update, perhaps as a mild nerf to the awesomeness of drugs - previously it was pretty easy to just keep everyone feeling awesome with no real drawbacks unless supply ran low.

But again: I haven't played in quite some time so I may well be misremembering.   

[scriver]

Hey, do you still get a bad mood from harvesting organs if you do it in the brief period captured criminal/raider is "considered guilty"?

[hector13]

I don’t believe so, but I only did it the once, and it was the heart so I’m unsure if it counted as an execution.

[Trekkin]

Hey, do you still get a bad mood from harvesting organs if you do it in the brief period captured criminal/raider is "considered guilty"?

Yes. As far as I know, the reduction in mood magnitude owing to guilt only relates to killing them.

[Majestic7]

Harvesting organs and selling slaves is always considered an atrocity by everyone who isn't a psychopath. I'm not certain if cannibals mind organ harvesting.

[Trekkin]

Harvesting organs and selling slaves is always considered an atrocity by everyone who isn't a psychopath. I'm not certain if cannibals mind organ harvesting.

I can confirm that they do. Psychopaths don't care, of course, and colonists with Bloodlust also won't mind the harvesting of prisoner organs.

Cannibal's effects are surprisingly narrow; they're immune to "butchered humanlike", corpse observation, and of course the cooking and eating of humanlikes, but beyond that they're normal.

[Deon]

Someone was talking about chemical damage here?
I can provide you with some.

[Dutrius]

I've recently started playing a game of Rimworld. So far so good...

...Apart from a nearly lethal heatwave early on, a malaria outbreak which took two of my three colonists out of action for nearly a season (one of whom is my doctor and farmer and the other my hunter, and the remaining colonist couldn't farm, harvest or cook). Meanwhile all my crops were taken by blight, and toxic fallout was wiping out all creatures on the map. When that finally passed, it was late autumn and too cold to grow crops. I had literally just enough food to get an indoor grow zone up and running long enough for a crop harvest.

No one has died yet, so everything's going well so far. This was all Cassandra on Medium difficulty.

[Akura]

This was all Cassandra on Medium difficulty.

"Uh, hey, Randy? I have to run to the ladies' room real quick, can you take over for a bit?"

"Sure, Cassandra, suuuure."