Actually I will pose an question to New Guy:
Are you utilizing all the tools available to you, such as staves, enchantments for better equipment and the other schools of magic aside from destruction? To only utilize destruction seems akin to a warrior only using a combat skill with no enchantments or equipment upgrading. I'm sure The dynamic is different when the best possible mage is pitted against the best possible warrior.
Granted people will take that last sentence to a literal breakdown of the stats to reveal the absurd nature of equipment upgrades and enchantments, so this will be a vague question at how one forms comparisons.
Yep. I make a ton of magicka regen equips, use conjure dremora lord along with that double summon perk to cushion up damage in real combat, use shouts, ebonyflesh spell, etc.
In short, I buff myself up to the best of my abilities, but then again, I was just testing sheer damage output and see how fast I can kill an enemy with the least amount of attacks.
So far, magic is at the lowest of the chain, bows in the middle ground, swords/onehanded enchanted weaponry at the top. The incredibly powerful enchanted dagger mixed with sneak and some other damage enhancement perks is out of the question though, being the best in sheer damage output if you weren't seen.
Admittedly though, I haven't spent my time crafting incredibly powerful alchemy equipment to enhance enchanting further, since I can't afford all that grand soul gems I'd need to make the best equipment, nor do I have the time to invest on that.
Speaking of Alchemy, I haven't delved into that greatly, since most potions tend to clutter my inventory, and it's a bit annoying to find the potion in an already cluttered favorites menu.
My final verdict is that if you invest in heavy armor, get daedric equipment and use two highly enchanted weaponry, your game becomes a no-brainer, which isn't really all that good if you consider some things.