I disagree with the notion that the loot boxes in SoW don't impact the players who don't buy them. There has to be a degree of rarity to the contents, otherwise noone buys them. The choice of loot boxes specifically as a pay-for-loot mechanism is also very telling, as they're highly tied to the existence of very rare items.
Being able to grind currency in-game to get the boxes is not the default design. If there were no loot boxes, the loot would just drop from bosses. I guess it still does, but there is a very high chance that the best way to get the awesome drops is to farm currency and buy boxes. That's the microtransactions driving game design right there. Treasure orcs? In no way would that be a thing if the market and loot boxes weren't a thing. Having a loot pinata orc type is weird.
And to repeat, for me the worst part isn't the existence of the market and loot boxes. Those things are fine in a free-to-play game. But they are putting these things in a 60 € game. I like my single-player games to be self-contained pieces of entertainment. I pay for them, hopefully enjoy them, then buy expansions and DLC if I did.
To be fair some of the corporate folks behind this probably think adding microtransactions is a purely service to players. While they do like generating money, they're not gamers at heart and don't understand how including these things can taint the game design. More stuff to buy is a good thing right? More content? Pay to skip boring stuff? How can that be bad? Well, it's bad because to even add them changes the core game play experience. I can actually forgive business people for making this mistake - but I can't forgive the game designers that I know are pushing for this, and have been for years. I've met them, and heard about the vision of gaming they represent. It's all about appealing to instant gratification, shallow game design and focus groups. It's not the kind of games I want to play.
I hope my suspicions are proven wrong and Shadow of War is an awesome game, where you can indeed ignore the market and microtransactions, and still have a great experience. But I am going to wait for the reviews.