My experience has been that the game does still have a bias towards placing opposing ethics at game start. I created like 40 custom empires and I really enjoy them over the rando ai, even if the surprise of random ai is fun
AI, when they first make contact with you, will default towards harming relations. It's only after the game develops more that they chill out. You are the default threat until they find a new one.
I've noticed a difference in my first contact protocols. When Im at 'aggressive' Im barred from many of the more positive interactions. However, it allows me to camp chokepoints and chase off builders when I am aggressive. Which I appreciate.
Taking an unknown starport no longer auto-completes first contact either.
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Im a bit of an aggressive expanded, with a preference for early game expansion. I tend to gear my early economy up through trade and then leaning on the market. I overproduce consumer goods as a byproduct of alloy production, and then sell those too.
New worlds are turned immediately into forge worlds, and I tend to skimp out of starbases for a while to build a competitive fleet. Early game starbases are generally more useful as forward defense than for their trade value, imo. Although Im also a huge fan of the food production slot on starbases. Less farmers means more smithies.
In general I overindustrialize my homeworld early on, and gradually turn my homeworld into a research and food world as the game progresses. I also probably underinvest in tech early on. 2 research buildings, 3 if Im doing well. I feel that the game is actually just an economy simulator, and if youre having trouble keeping up with the admittedly cheater ai than you just have to buckle down and burn your economy harder and earlier.
The ai tends to outtech me anyway, its just that I tend to focus on going after stronger branches in the tech tree while they do everything. And the warmonger ais are almost always at least superior to me, because Im expanding well into the mid game if I get my chokepoints right.