The fact that there are like three types of ton(nes), (short, long, metric) kind of pisses me off, just come up with a different name for all of them already, it would be like having a imperial kilogram just to confuse people.
While the default is usually metric, the default unit for ton is imperial.
EDIT:
Something moving that fast and that large would be a really good weapon though (although increasing the speed and making it smaller would probably be better). It would be very hard to stop (with anything near our level of technology at least), probably fairly hard to detect (since it would be moving so fast), and deal an massive amount of damage, it wouldn't damage the physical planet that much, but it would easily cause a extinction event, and kill off the majority of humans without a real problem.
I don't think we could damage it with our current level of technology, by the time we notice it, it would probably hit us in less then two days (since I don't think we would notice it much before pluto).
Traveling from the moon would take it 10 seconds, and we couldn't conceivable get anything farther then that without years of planning (which we wouldn't have). That means that we would only ever get a single chance at it.
You also have a pretty slim chance of hitting it, its going very fast, and space is so huge that even a 4000 ton spaceship would be immensely hard to hit, especially when its going so fast.
Now, how much damage a missile could do depends on its configuration, but I think that if it was being used as a weapon (otherwise you wouldn't aim it directly at a planet and have it go .1 of light speed), it would be purposely hard to destroy, having it be long, with fairly thin walls (so a projectile would just punch through), and no atmosphere inside (so nothing would rip it up and destroy the ship with it).
Even if you hit it with a nuclear missile, you wouldn't do much damage, the missile would just punch a hole straight through, and it would already have escaped the explosion by the time it went off.
That said, if the missile did hit there is a reasonable chance that it would get nudged off course and miss the planet.