(A bit ninjaed, as I tried to reduce tue waffle, and probably failed.)
In general, the major difference between Linux dists are not in the 'commands' (i.e. anything you'd do with shells, saving perhaps
precisely what shell-based install command to use), but in the 'skinning' of the GUI. The package-manager interface[1] may vary a bit, but within broad 'wizard'-style bounds that make adding (and removing) functionality not really an impediment for most[2].
Once installed, GIMP is GIMP, LibreOffice is LibreOffice and that Asteroids-like game is that Asteroids-like game, no matter what wm you have (by necessity, default or choice). KDE/Gnome/whatever-based might change some of the support issues you encounter (basic apps might be KDE-specific or Gnome-specific, which might mean hoops to jump through on a basic system install), but being (potentially) as simple as Tom's/Motif or going into the Ice/Xmonad/xfce/etc is mostly bells-and-whistles (like the trend to go for the fancily rendered 'desktop furniture'). And you really don't need glorified "scrollable horizontal ribbon toolbars",
a la Apple, when a (now) basic "Start button on a toolbar" gives you much the same (whichever edge/corner of the screen it inhabits) in a way long-time Windows users should be comfortable with.
(
Really minimal distros might not even have a 'classic toolbar', instead you pop up a menu by right-click on the desktop, but even Puppy/Damn Small Linux (both JWM?) these days seem to include the toolbar/'start button' setup.)
If it really needs to be reconfigured to work, any half-decent thing (under open-source development) probably has had someone do the necessary work just so that it works for
them.
Of course, closed-source products may be beyond use (unless WINE/etc helps). And when you're dealing with someone who gets confused when a "small icon" view is changed to a "details" one[3] then it can be a bit of a hill to climb to get used to a more widely revamped appearance
and having to switch away from MSOffice to Libre and/or Photoshop to GIMP (advantages to both aside). Even if OOTB or trivially-reconfigured-OOTB
functionally does exactly the same.
Horses for courses. Dists for lists (...of highly personal pros and cons).
[1] Assuming you didn't go straight to one with negligable out-of-the-'box' GUI, and even then you tend to get 'ASCII-rendered' pseudo-GUI setup and package installation tools so you don't need to do more than click-or-tap your
[2] In fact, my past tendency has often been to go "I want that, and thst, and that, and
definitely that. Let's also try that, and I can always remove that later...", which was always a developing problem when disk space was a premium.
[3] Actual experience of that... If I switch it, e.g. to sort/examine by file-size, I
need to remember to change it back before handing back..m