No, if you expect the other guy to take 50$, you really should take 50$ because that's the most you can get in that case.
Well, yeah, if you really expect the other guy to do that, sure. If you're widely known as a douchebag, and thus have a reason to assume that the co-player would assume you to pick 50$, you probably should pick 50$. However, reading the wikipedia article for the game, that's not really a reasonable expectation most of the time.
A lot of people think "more money = more better" and just write a large amount. A lot of people will be willing to risk it and assume the co-player to cooperate to an extent, and write a large amount. It kind of depends on whether you are playing the game with a person or a being of pure logic.
It also depends on whether you can afford to lose. 50$ is just low enough that I'm somewhat okay with not getting anything in the event that the other player does choose that. The only way to win, assuming you aren't the insurance company, is not caring about the outcome.
It probably becomes more glaring as the bonus gets smaller. It seems the classical example is a range of 2 to 100 dollars. In game theoretical terms, it's the exact same situation, but for some reason virtually no one wrote down two dollars.
it is pointless to demand 200$ unless you have a real reason to believe that your opponent will demand the same (and even then you could optimize by lowering your request slightly to gather the bonus at the other guy's expense). If I got 100$ for someone who greedily just wants it all, I'd consider the other person stupid for not thinking his strategy through.
I'm assuming that the other guy is probably going to demand somewhere over 150$, which doesn't sound unreasonable to me, and don't really mind losing if I get more than a hundred bucks for it.