Report exists for a reason. Don't listen to the people crying about tribunal being flawed, if you go to any county jail you'll hear hillbillies saying the same shit. If they're being gratuitously toxic, report them.
As for Vayne:
I use all flat AD runes for better last hitting, but that's definitely not the optimal setup for a competitive environment. Vayne's a very weak laner pre-6, post-6 and with some items her damage and mobility makes her really good at killing people who don't play carefully.
Boots, dorans as necessary to stay competitive in lane. Don't go overboard on AS, even at maximum attack speed her W isn't nearly as powerful as people think. IE or BT first. IE if you have good teammates and a sustain support and know you can get by without lifesteal for now. In solo queue you'll usually end up with bloodthirster. After that phantom dancer. That's the core, and after that it's situational, but my completed build was usually Boots, IE, PD, PD (At two PDs you can probably get rid of boots if there's something else you want), BV (Nowadays QSS has overshadowed BV as the carry defense item), BT. As always, you have to be flexible. I haven't played Vayne in quite a while so this may not all be 100% accurate anymore, but I don't think she's changed significantly aside from losing some of her chase power.
Flash is obviously mandatory, for carries the second summoner spell is usually either Heal, Cleanse, or Ignite, with a sort of rock paper scissors deal. Heal counters cleanse, a heal carry will always win exchanges against a cleanse carry. Cleanse counters ignite, ignite counters heal. Exhaust is also a decent choice, especially on a close range duelist like Vayne. I can't think of anybody who can 1v1 a Vayne with exhaust on equal terms.