Entered the scenario with one pre-dread battleship and three destroyers chasing a damaged cruiser which had been raiding my shipping near Panama. Ran into no less than four more heavily armed and armored British battlewagons, which promptly led me to attempt to flee to port. Their opening volleys managed a lucky hit that just barely missed the rudder, leaving the USS Michigan swimming in circles until damage control got the rudder unjammed. In that time, they managed to get enough hits to be counted only on one hand on the Michigan, while the Michigan crack gunnery crews proceeded to rip the daylights out of the poor Repulse, which managed to get trapped somehow in the chaos of battle between Michigan and the fleet station in Colon. We disengaged, the Brits won the seas but were left to limp away, leading to the scenario assessment to treat it as a US minor victory. Considering my sore lack of experience with this game, I'm rather pleased.
EDIT:
During the second Anglo-American War of the 20th century, an American armored cruiser (USS Huntingdon) and four destroyers had the ill luck to encounter an enemy raiding force of three light cruisers (HMS Cordelia, Calliope, and Calypso) and three destroyers off Halifax while patrolling between American-occupied Newfoundland and Bangor. Ordinarily, this would not have been awful, the Huntingdon being designed to chew up anything short of another cruiser class (and even give those a good showing). However, save for the fact that due to a storm, the two forces encountered each other within torpedo range, leading to the Huntingdon taking a solid torpedo strike amidships from the HMS Foyle within the first minutes of battle. Not willing to let the British escape to raid American shipping, the captain of the Huntingdon proceeded to direct damage teams to control the flooding over the course of the next hour, trap the raider force between himself and Nova Scotia due to their overconfidence, then rip them to shreds with concentrated fire from the four 10-inchers and 22 six-inchers. Just to add insult to injury, the Americans proceeded to loiter long enough to retrieve all British survivors they could from the sunk ships before departing. The only British ship to escape (to Saint John) was the HMS Ribble, and even it arrived with heavy damage. The American battleships might not measure up, but the British shall rapidly learn to fear their cruisers.