Is he talking about dogs or crusader kings? I'm so confused...
Allow me to make an explanation, in creatures 3 the main focus is on raisng norns, you can mess around with ettins and grendels too but usually it's about norns, there are all kinds of different breeds you can download and some of them are very unique. Anyway the norns you start out with have a very basic vanilla code that tends to make them very boring and average, with no abnormalities at all, but over time with breeding the code mutates and you get all kinds of different breeds, the genetic code in the game is extremely complex, you can wind up with norns that have extra strong organs, or extra weak ones, or ones that digest food better.
The same applies to mental attributes, you could have an extremely fast learning norn, or a very slow one, or a bipolar norn, that cycles between being angry and happy, or a norn that is just naturally happy and non-violent all the time, I once had a norn that literally could do nothing but eat and sleep.
I'm not kidding there didn't seem to be any other kind of mental capacity in it, it couldn't even talk. It was like those children that fail to develop brains and just cry all the time. I had to wake him up to make sure he'd eat, and after he ate he'd go back to sleep, unless he still had more food to eat, he could keep eating indefinitely and never stop till he ran out of food. In the end he died in a somewhat disturbing way, one of the other norns was constantly press the button that spawns more food, so he wound up eating something like 20 pieces of cheese... I assumed it gave him a heart attack or something because he passed away not long after that. So yeah... mutations, they make the game very interesting, and most of them aren't like that.
Oh and the wolf running thing, that refers to when you use a program to speed the game up really fast, so you go through several hours of gameplay in 30 minutes... usually this is done overnight so you have days worth of norns breeding and evolving.