Enjoyable game... Managed to come out on top in Germany, obviously and now I'm one province away from creating "Germany" and once I get my Infamy down I can try and make the entire HRE my vassal.. of course I know for a fact that Burgundy won't like that so may end up as an epic HRE Civil war.
The eventual war with Burgundy should be interesting though, besides Castile they are the only major power I haven't fought.
I also bit the bullet and started Colonizing as you can see by New Hessia, They should help a bit in any Mainland Conflicts
On to Observations:
Great Britain got bogged down in European wars I think so they couldn't become that much of a Colonial Power, but since they've decided to focus more on peace they've picked up the pace in that department, though its looking like the USA will be in Mexico and Mexico will be where the USA is supposed to form.
Castille has pretty much ignored Europe beyond annexing Poland in favor of trying to colonize as much as they can.
France... well their holding on, probably thanks to being in the HRE, It looks like their abandoning Europe in favor of a Colonial Migration or something.
Burgundy.. well their burgundy... they've basically left Germany itself alone in favor of trying to unite France under their rule.
Aragon, They focused their ambitions on Italy, at one point having almost the entire place in their control, then I intervened shortly after being Crowned Emperor the result was a... bloody and long, not being strong enough to break through their lines and they constantly sending 2-4 unit naval invasions which of course got annihilated, but now they've been kicked out of Italy and its back to the hoard of minors par usual.
Scandinavia, not much to say about them, except when they war they like to send CONSTANT invasions of 1-3 units, to the point after my first war (Back when they were Sweden) I had 99 Army Tradition.
Prussia: Used to be a friend, now a Rival, fought two wars with them, first war was initially about forcing Catholicism on them (IIRC) and the Second ended up me forcing them to release the Teutonic Order (haha)
Teutonic Order: Formed into Prussia - > Got released thanks to me, then Pomerania Seceded and I was dragged into the war to defend them, resulting in a couple minors being released.
Austria: Or perhaps the Austro-Greco-Turk Empire, They utterly pwned the Ottomans and are a definitely major power, my first war with them however was a humiliating loss for them, but since then they've secured Asia Minor so its a scary prospect facing them.
So yeah... the 1600s are promising to be "Interesting."