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[10ebbor10]

Oh,yeah, that's it.

[ChairmanPoo]

That wasn't the issue; they weren't triploid mice. They produced X0 eggs from a male pluripotent stem cell line that had lost the Y chromosome. Apparently X0-derived eggs are viable in mice (this is not so in humans) which allowed fertilisation of eggs derived from a male stem cell line, with sperm from another male.

[scrdest]

That wasn't the issue; they weren't triploid mice. They produced X0 eggs from a male pluripotent stem cell line that had lost the Y chromosome. Apparently X0-derived eggs are viable in mice (this is not so in humans) which allowed fertilisation of eggs derived from a male stem cell line, with sperm from another male.

Still, even if it was viable, you'd have two germ cells with male-pattern imprinting, so the result would have genetic disorders of various kinds. Which is in fact why human cloning is not legal.

[Tiruin]

*hugs Sappho*

hope you'll be ok...

[Sappho]

*hugs Sappho*

hope you'll be ok...

Thanks. I was starting to think I posted in the wrong thread... Actually, just before I read this, I called them again. They did find the suitcase and it should be delivered tonight or tomorrow. Huge sigh of relief. My trip from hell is finally coming to an end, and I can get back to freaking out about normal things, like my appointment with the foreigner police on Tuesday, the big work meeting on Thursday, and how I'm going to pay all my bills after missing 3 weeks of work!

Actually, while I'm in this thread, there's something I realized while I was visiting my sister that really upset me. Well, there were a lot of things I could rage about, but this one in particular is on my mind at the moment. I have a very tiny apartment (20 sq m) in a very nice area of Prague. It has everything I need and I'm very happy here, but my sister and her new husband (and their 2-year-old daughter) live in a HUGE house. 3 bedrooms, 2 bathrooms, an office, a huge living room, and a gigantic kitchen. They told me their mortgage payment rate, and it's not much higher than what I pay in rent each month. They also have an obscene amount of *stuff.* New furniture, appliances, a closet full of towels, many cupboards full of various types of pots and pans and dishes and kitchen accessories, walk-in closets full of clothes, three computers, three huge flat screen HD TVs, full high speed internet and cable service, rooms full of toys for the little one, just... It was mind-boggling. I couldn't understand how anyone could possibly need or want so much stuff, let alone afford all of it! I could probably list every single thing I own on a single piece of paper, and I don't even have any savings (largely thanks to having to travel to America all the time for visits). My sister is a preschool teacher and her husband is a cop - not exactly hugely high-income jobs.

Then one morning I overheard my sister and her husband discussing their bills. They were choosing which bills they would pay that month, and which credit cards to pay them with. They have something like 4 or 5 credit cards and they don't pay everything they owe each month. That's when I remembered the culture of debt in America. I had genuinely forgotten about it. Where I live now, if you can't afford something, you just don't buy it. I don't think I know anyone who has a credit card here, at least not one they regularly use. If you want to buy a house or apartment, you get a mortgage, but you have to have a huge chunk of the cost ready right from the start or the bank won't even give you a loan. University is paid for by the state (through taxes), and people don't move out of their parents' houses until there's a reason to, like moving to another city or getting married. Just about everyone pays for everything in cash. It would never even occur to me to buy something I didn't already have the cash for. I still pay student loans every month (just a few more years!), but since leaving university I haven't acquired any more debt, and I plan to keep it that way.

I hated my trip to America, but I do like this sister, and my niece is wonderful. It really upsets me to think of them being in debt for the rest of their lives. Especially since they don't need to be in debt. They don't need all that STUFF. But it seems to be a basic part of American culture, that you buy the stuff you want, when you want it, and never think twice about debt. I can easily see my niece inheriting my sister's debt, many years from now (I hope) when she dies. Retirement is never going to happen. It's absolutely insane.

[Tiruin]

O_o

We've the same culture here in the Phil..like in Prague.

I'm really wondering where..err, that culture stems from. The credit card one.
Also did you advice that..some stuff seems like more luggage than one could carry at the moment? Everything doesn't need to be now.

[LordSlowpoke]

i'd just like to say

Spoiler: image, yo (click to show/hide)

the paella pan is a a fusion of the pot stand (only available from the artsy cuntwaffle for lodsemone afaik), a shark fin and 3 water shrooms. it's a tier 1 shield.

recettear's fusion system is literally hitler

i got louie to level 99 on ng+

actually no let me say that again

i got louie

to level fucking 99

you need over million and a half exp to manage that shit

[Bauglir]

Man, fuck debt. No credit cards for Bauglir, and I'm weaning myself off debit for purely psychological reasons (I manage money better when it's got physical form). I'm glad I got this one figured out because even if my credit score is tanking, I'm better off financially. The one debt I do have is still pretty damn crippling (I could work part time if I didn't have student loans), and I've got no interest in adding the last straw to that that would leave me in the death spiral of needing to borrow to pay off my debts.

[10ebbor10]

Actually, that has been statistically proven. People spend less if money is in physical form.

[Bauglir]

That's what called my attention to the fact that I am definitely one of the people for whom it's true, yeah. Point being, debt unnerves me. I hate the idea of not being able to make good on what I owe. So I hate owing lots of things. And while I accept the necessity of debt for some things that will make me money in the long run, getting into debt for the sake of just having stuff around the home seems bizarre to me. If I can't afford a lifestyle with the money I have on hand, how can I be sure that Future Me is willing and able to pick up the difference? Especially when I can't figure out how most of these things would meaningfully improve my life; smartphones will never cease to confound me.

[kaijyuu]

I'm very much NOT a materialist so I don't think I'll have much in the way of debt. School is being paid for by parents, room and board currently being paid for by wife's parents, and I simply don't buy anything very often. Later in life, I'll probably build a house and go into debt for that, but I'm absolutely certain I'll be able to pay it off in a reasonable amount of time.

I don't care about stuff. I care about experiences. I can get those without stuff.


(notably I'm very hard to buy presents for. This christmas it took forever to find me something I'd actually use; eventually settled on an uninterrupted power supply for my computer. In fact my computer is pretty much the only semi-expensive thing I spend money on on a regular basis, and pretty much entirely because it provides experiences through video games, online friends, etc, and not because it's a thing I like owning for its own sake)

[Frumple]

I can easily see my niece inheriting my sister's debt, many years from now (I hope) when she dies.

For what it's worth, don't worry about this one too much. Most debt cannot legally pass on to family in the case of the debt owner dying. There's exceptions, but not too terribly many (and, iirc, most involve cases where the debt is attached to the estate rather than the person. If push comes to shove, it can be ditched by ditching the estate.). It likely means losing certain material goods -- stuff legally owned by the debt owner on death will be liquidated to pay off debts -- but the remaining debt shouldn't transfer (assuming the debt collectors don't attempt skulduggery, anyway. Lawyers might be recommended at that point, just in case.).

And... to be fair, that kind of behavior isn't entirely universal in the states. We're definitely somewhat cavalier about debt (and somewhat resigned to certain ones, such as student loans, never going away), but situations like the one you described is... well, not exactly uncommon, but not exactly the standard thing, either. Least from what I've seen. Folks do know juggling debt like that with multiple credit cards and whatnot can (will) come back and bite them. Fairly often, anyway.

[Iceblaster]

Damnit.

See Fallout NV ultimate edition is $20 on Steam, yet I cannot work up the courage to ask my dad because either I'll get 'You already have it for the Xbox, can't you be happy?' or 'I'll think about it.'

Both mean no and even in the case I did ask there's also the problem of convincing him to even pay for games *gasp* online because for some reason he has an aversion to buying things without a physical copy

Sure Minecraft and all is fiiiine.

Probably worrying too much though...

[Sirus]

Regarding debt: I have two student loans to pay off, plus a credit card which I sometimes use. This is quite a bit, but nothing on the level of some folk's debt. And since I have very few ongoing expenses (food and cell phone, basically), I put a not-insignificant amount of each month's income towards paying them off. I am very much a materialist however and the reason I keep relatively few things with me on the road is out of necessity, not choice.

Unrelated rage: Once again I arrive early to a delivery site only to be turned away. This time it is slightly more understandable (I'm really early), but t does get annoying because some places will take you early, others won't, its impossible to know which is which beforehand, and I always shoot for being early instead of right on time. My professional pride is at stake here, people :x

[Vector]

I use a credit card almost exclusively, but I don't have any debt, have never missed a payment, etc.  Pretty much all of my monthly expenses are food and housing.