If you're looking for seclusion, I just got back from scouting the terrain across the County highways of Nebraska, Kansas, and Oklahoma. Plenty of room, plenty of lots looking to sell, probably for very little money, and shoddy old building to refurbish or hide prefabs behind. Totally private, because every other house is right at human-eye distance, and surrounded by trees, when you can see each other at all. Forget growing anything, that takes too long and too much land. Instead, it's prime country for building windmills. Even a private sized one could easily mean free electricity (and because well-water is mandatory, free water). Enough land (not very much), and you could even make money selling the electricity. Or just lease the land for a real company to build turbines on; ditto for leasing the land for cell-towers, radio towers, gas wells, and other such "eyesores". If you're dead set on farming, it's more than secluded enough for drugs, but there's definitely no good market around.
CONS: The land probably isn't that cheap, and the capital outlay is enormous. All Internet is satellite only, and the weather can be brutal even without tornadoes. It's a three hour round-trip to the convenience store, and God knows none of us can subsist on vegetables. The nearest computer hardware store is an all-day affair. And we'd look pretty out of place, with our glasses, frail limbs, long hair, luminescent skin, and varying dictions, among the sun-burnt human doughblobs who populate the area.