Just in case:
http://forums.bethsoft.com/index.php?/topic/1123460-potential-fix-for-npc-slowdown/
Wow, my PC slowed down to hell when I saw multiple NPCs, now I can finally play. Thank you Soulwynd
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Exploration and landscape:
What does the "new" wasteland look like? What has changed? Has exploration remained similar to FO3?
Crafting:
How complex is the crafting and gathering system? (I've seen comparisons to Morrowind&Oblivion, and I simply loved the Alchemy skill there)
Hardcore mode:
How well do the features meld into the game? Do they provide a nice challenge or are they just tedious? (I'm fond of survival games and FO3 has been to easy)
1) Well it's similar to FO3, but the look of the land is much closer to "Amerika" to me. "Capital Wasteland" in FO3 seemed... wrong. Also there're conveniently placed mountains which make you to travel far though dangerous locations, and landscaping is pretty neat. So far I enjoy it. Plus there're much more variable factions, and with a new feature to wear faction armor as a disguise you can walk different routes for safety (well, unless you fast-travel... I don't). So it's quite interesting.
2) The crafting system has quite a lot of ingredients and products. I wasn't using it too oftem, but sometimes it's handy. Although you have to remember components for required items you want to gather, because you can only see the "recipes" at specific workbenches... I am sure I will either remember them or find a mod or a FAQ with a list of recipes. However you can get followers which act as "workbenches" so it's not that bad further into the game.
3) After a few hours of play, I must say that Hardcore mode is pretty easy (there's a lot of food around, and water too), but it's a must-have for me. The requirement to look for doctor bags to heal crippled limbs and other features like that make combat tactics much more important. Food/sleep/drink part is really easy to satisfy though.