somebody has a real attachment to AMRs...
Anyway...a couple of suggestions.
Sentient Machines, Animals, & Plants - we have a few Examples; Skynet, President Eden, Brain, Keeng Ra'at, Goris, Seymour, the Professor's Radscorpion, and Talking Brahmin. They either form their own civs (Goris' Brood tried to, and Skynet talks about "settling down and starting a family") or even take a leader position of another civ like Brain did.
Magic - Ok...hear me out...In Fallout 1, The Master was a Psyker and collected other people with psychic abilities. In Fallout 2, Sulik could consult his ancestors ghosts for clues regarding your current quests, The Elder and Shaman both contact you via dreams, and you even have a short quest where you meet a ghost and she asks you to bury her bones so she can rest. On the unfavorable hand, The Chosen One is a Tribal...as well as the Shaman's apprentice...so it might just be years of abusing Healing Powder catching up on you.
Sand Sharks - cut from Fallout 2... and Van Buren(which itself was cut in its entirety) ... and Tactics... but... C'mon... Sand Sharks!
We'll have to wait for the next DF version maybe to make a difference between natural mutationI(6 fingers!), radiation exposure(ghouls, humans with a rare genetic trait that manifests on normally leathal radiation exposure), and FEV(Super Mutants, The Master, Harold, and other "factory made" mutants)...also every creature on the surface except Vault Dwellers has been exposed to a mutated version of the FEV that in most cases just boosts muscle mass and intelligence(except in dogs and humans for some reason...) but does not cause sterility. Lesions and patchy fur might just be due to the high radiation environment and not FEV
Fallout Wiki says...the sterility might be due to "double dipping" as it were...an FEV overdose.
And Lastly, get rid of Mobile Factories...they're really just a waste as you can buy the robots you want from caravans without waiting for the thing to pop one out and hope it's the right one...The guy that came up with that is a moron...oh wait...that was me... ... ...I still stand by what I said.