A few things on that design:
I think your fuel capacity is a bit low, 217 days isn't a great deal of time, especially if you're going to have the ship out patrolling or during TF training, given that you're going to have nearly 5 and a half years before needing maintenance supplies, you're going to be refueling about 6 times for every supply pickup. Unless you are going to have the ship in areas where fuel is common but supplies aren't it's a bit of a waste of supply capacity.
Your ship has no defenses. At all. 4 Layers of armor and 4 Delta shields will give you very little protection, a couple of missiles will probably destroy or disable the ship, I'd either add some CIWS or P.D. energy weapons (perhaps trade missile launchers).
Your missile fire control outranges your active sensor by nearly a million kilometers. On top of that, the active sensor is resolution 100, which is normally better used in long range scanners as you wont be able to detect (and therefore target) smaller ships until they are right on top of you. I'd say you are better off having a lower resolution sensor on this ship but having another ship with a long range, high res scanner.
Other than that it's a nice design.
Also: with regards to the point defense wiki page, I have looked at it, and you have covered the DESIGN of the 3 layered point defense, but I'm talking about actually setting them up for optimal coverage (e.g. ratio of AMM/weapons : fire control, some examples of good mixes of point defense mode and range).