I joined yesterday, and am planning on heading down the abomination route. Any suggestions on when I should head to the necropolis, or anything else I should know?
You have alot to think about before going abom. Consider this:
By the time you become a hideous freak, you can no long live in freedom city safely. C3-50s bots can break into apartments and kill you, and they can track you down for some time even after you're away from cams, don't forget hideous freaks are considered monsters and are attacked on sight by FCPD, unless you happen to be very good with sneak. Also, you'll never be able to buy from most stores, so you'll need a reliable friend to buy you cocoons and related stuff.
Hideous freak also comes with an annoyance: Mental diseases may aflict you everytime you clone. They go from silly random shouting to considerabl debuffs to your cool, brains and focus, and even endurance and senses. A experienced doctor can heal that for you by psychoanalyzing you, but you gotta do it fast before they develop, or it'll take a seriously skilled doctor to take it off you.
You clone randomly resets to the necropolis, doesn't happen often, but it does actualy happen once in a while, and it can be a real pain in the ass if you can't get past the group of deadbots on the way out (that one attacks even freaks). Things get considerably easier when you become an abom though, but even though you get awesome soaks and abilities, don't forget you can't use armor thicker then 4, so no deathsuits, kevlar, caballero, armordillo or practically any other kind of proper armor. You can still layer leather stuff on yourself and other cool stuff though to get some nice soaks (leather stuff, robes, trenchcoat, even a goddamn deathshead).
Unless you really know what you're doing or have considerably skilled friends that you can trust, I don't recommend becoming an abom.
Being an abom is pretty fun though, if you can cope with the hideous freak stuff, just remember that blades don't work nicely with an abom, much less guns. You'll be limited to fists, spears and clubs. You can technically still use whips, but why you'd use whips when you can use spears, fists and clubs with great efficiency is beyond me.
Also, protip: Don't grind dodge, its not worth it. Just gain XP and learn it from an NPC or player.