I played all of IC. I liked the name someone gave it, "Impossible Lobsters", specially because it was so true, the best creatures were those genespliced with lobsters (great armor, swimming and regeneration).
I think regeneration should be mandatory for all units in all RTS's
(even if it's only up to half health or something... even tanks). I remember that martial arts RTS that is so awesome, wossname, Battle Realms... I hated micromanaging the healer geishas, and Winter of the Wolf expansion added a warrior/barbarian faction that had no healers but where every unit had regen. The campaign was kinda awful but the regeneration made it more playable.
(any strategy game where peasants start going kung-fu at your spearmen ass if your try to invade is awesome)
Which brings us to... organic technology. Yeah. What do you do if your spaceship starts dying of prostate cancer?
EDIT: That reminds me. In the RPG game Buck Rogers: Matrix Cubed (sequel to Buck Rogers: Countdown to Doomsday, which is a game that everyone should play. It's like one of those old SSI gold box D&D games such as Pool of Radiance, except that it doesn't suck, and it has rocket and plasma launchers and all kinds of sci-fi weapony goodness), at some point of the game you have to get into a huge organic ship to get to Jupiter or somesuch - previously in both games you were able to pilot your own rocketship around the inner planets and as far as the asteroid belt, but for some reason it was stated that the outer planets were just too far away to reach with normal ships... so yeah, organic ships. I guess they eat void or something.
Anyway I liked that it was realistic because a lot of that "act" you had to solve problems like sabotaged (severed) nerves that you had to fix with Doctor skill instead of repair, and make antidote for the poison it had received or some sort of virus. Also this ship wasn't conventional in the way that it didn't actually engage in spacefights, it was a plot ship. The sphincter doors looked also kinda funny.