2) Focus on getting out of the dungeon. Your food won't last forever, and you can't find much food or equipment in there. You can return to clean the dungeon out later.
That's the main thing. My prior roguelike experience was mainly nethack, so I tried to complete each level as I came to it. It doesn't really work that way in Legerdemain, though. The other thing is the layout is not procedurally generated, so you can use what you discover on one character to help you find your way out and get to an inn.
Also, you can exploit the slaves in the first dungeon; they won't really follow you very far, so you can lure them away from the pack one at a time and kill them that way.
I just started a new Bios during lunch... and now I know luck can play a very big part too.
The first monster I saw is a light-grey "i". I didn't care to find out its name, because it was hitting me very hard! And it won't give up chasing me. My biggest mistake was I didn't immediately memorize my healing spells.
It was right outside my prison cell, and I had to run in circles. Its speed matched mine - despite my full speed fleeing (I vaguely remember the correct way), it still bit me plenty of times, enough to bring me down to 3 hp. It chase me all the way to the "less civilized" junction, and then a bit more. I got rid of it by bumping into a bunch of r's (rats), q's and u's. It probably couldn't path to me.
When I made it outside, I was chased by another mob - 2 b's, 1 S, 1 u, and on my way running to the village, 4 more b's. And all I've got is a piece of wood to smack them with, no armor.
I made it inside with 2 hp left.