I hate canned laughter. Let me get that out of the way. This trailer's use of canned laughter drove me insane. Now, onto the gameplay.
1) Pacman: You go around eating things that look NOTHING LIKE YOU!
2) Second stage: Ocean Pacman. You go around eating things that look NOTHING LIKE YOU. In the 3D Ocean! Compete against other creatures!
3) Third Stage: LAND Pacman. You go around eating things that look NOTHING LIKE YOU. But this time, on Land! Compete agianst other creatures!
4) Interesting creature creator engine. Too bad I
don't really care about creature creation, because I prefer to actually play a game.
5) The Interesting Leveling System within the creature creator engine seems interesting, you gain more creature body parts as you level up. Still, let see gameplay.
6) Sex. That was...unexpected. Um...
7) Finally. The game has mutated from "PACMAN" to "POPOLOUS"! Now, I run a tribe, and no longer have to go out and play Pacman.

The game designer has taught his creatures a war dance and gave them weapons. Now I'm getting interested.
9) Game morphed into "City" when you upgrade your little hut.
10) WOAH! Guy just clicks on "Build Stupid Building", and a "Stupid Building" pops right out of thin air! With nobody even building it! That's just awesome! I wonder what sort of 'procedureal generation' was needed to have my race learn how to pop stuff out of nowhere!
11) The developer is showing off a building editor. Eh. I'm a lazy guy. I don't like designing buildings that much...meh.
12) The developer mentioned about how happiness is the key indicator about the success of his city. Eh.
13) Developer just showed the enemy forces, which is the exact same species, only slightly modified, but running a very aggressive techno-futuristic dictatorship. And they are sending tanks our way.
14) There's an ARMY EDITOR? How many editors are in this game anyway? Are these developers thinking that there is a horde of people just wanting to tinker with itty bitty creations? Give me the defaults! Oh well, I guess an army editor is at least more functionally useful, since you will need to have a tailor-made army to take advantage of enemies' weaknesses.
15) Our new army are revealed to be "peaceful cowards". Idiots.
17) The explosions of my town getting blown up is nice. Very nice indeed.
18) Developer is revealing tha the City mode is turning into the Civilization Mode now. Developer states that you can control how much micromanging I want to do by zooming out or zooming in. Zooming out looks very...surreal.
19) The developer called it a day...even though his city was being blown up! Save the city from those tanks!Please, save them! Gah.
20) Anyway, the developer skip-fowarded. He bought the instant-win button, the UFO. The UFO magically appeared out of nowhere, clearly a sign of the hyper-advancement of my pacifist race.
21) UFO has abducted some creatures. What is he going to do with them?
22) WOW. Turns out that you don't have to beat the other civilizations to become a space-faring empire. All you have to do is buy that super-UFO. Then, say Tally-Ho to your civilization and set forth!
23) Planets in the solar system are being described as "sandboxes". That's never a good sign.
24) So he's going to use the creatures he abducted to...populate a nearby planet. He first has to give this new planet the ability to support life, of course.
25) I wonder what's happening to my own Civilization that I left behind back on my home planet. I hope they are doing quite well, and not standing there motionlessly while the techno imperimum bomb sends tanks.
26) The terraforming system seem actually very interesting indeed. Of course, I'm sure that's the first thing Maxis took out when releasing Spore.
27) By the time you can colonize space, you also can colonize the ocean, thereby removing the need to actually colonize space. Eh. As he said, the planets are "sandboxes". Not really important.
28) The Developer admits that the only reason to care about your civilization now (like building colonies) is to earn more money to upgrade the UFO. Wow. So the civilization exists only to fund the UFO? That's a rather...interesting..."concept". Talk about the UFO-industrial complex.
29) Terraforming is doing its job and looking pretty nice. Developer showcased the Genesis Device, a thing that allows you to instantly terraform a planet, but he said it would be very expensive.
30) I have to earn a ton of money to buy the Interstellar Drive, which allows me to travel around the universe. What's happening on my home planet?! Gah.
31) The developer has discovered another intelligent alien race by listening for radio signals. Time to send in the UFO to
kill explore!
32) Developer plays the "First-Contact MiniGame". Developer loses the "First-Contact Minigame". Hilarity ensures. Developer then deploys the Planet-Killing Device, looking cool, but still...meh. It just means we have to find another radio signal. Would have been more impressive to have genocided those aliens peacefully and then placed more colonies so that we make more money.
33) Developer was happy that he created a ring of debris, but he himself stated that there was "Nothing more to see here". Meh.
34) The developer is just ranting at this point, talking about creating monoliths and making diplomacy. I guess those features hasn't been coded in yet. All the editors are accessible, meaning I can now create "hybrids" creatures...though I guess there is no reason why I should make them.
35) The Space Stage in Spore is supposed to be the main purpose of playing Spore. Everything else is just the 'tutorial'. The Space Game is the ultimate sandbox, filled with metagames such as diplomacy and creating zoo planets. The developer also handed out concept art, altough since I was looking at the gameplay video, I didn't see any concept art.
Wait. If the Space Stage is the actual game, and everything else is admittingly one long drawn-out tutorial...Oh god no.