As an ethnic Russian, I have nothing to gain and a lot to lose from Tomsk gaining independence.
Why, why are you so sure of that? Let's look at this from a practical standpoint. Tomsk region is too small (well... It is around the size of Poland but...) to go independent alone. Let's look at a more realistic independent state, large chunk of middle Russia\Western Siberia spanning from the Arctic (giving access to the sea) to Kazakhstan, China and Mongolia.
This will be a country that is rich in natural resources (including oil and gas) and quite low population. Being independent from Moscow, all taxes and profits from natural resources will stay there. Rest of Russia will need to actually pay for this resources to keep their factories running instead of taking it away for free and giving some meager federal funding in return. Yes, this new country will need to pay for the transportation of oil and gas through new countries but those are minor costs. Oil and gas flow can also be redirected to China (China will happily help building pipes if needed)
If this state will keep some nukes, it will be absolutely safe from any invasion while having no need to keep a huge army. Also, there will be no need to pay for Pacific\Baltic\Black Sea Navy or for military operations in some Middle Eastern countries.
Direct trade (without caring about Moscow's political and economical interests) with the economical powerhouse of China will be far more beneficial for local people, too. And sweet customs money will go to the locals, not to Moscow. And locals will also get money for goods transiting through their territory from China to Moscow.
Also, let's not forget a minor convenience that when Moscow will choose to start a new war, locals won't need to go and die in places 1000s km away from their home...
Your life would be way better in such a hypothetical country. Barring some minor inconveniences like needing to cross the border to visit the warm beaches of Sochi
PS.
Just because I want a free Russia doesn't mean I should want to give a small minority their own states. The Siberian natives are literally irrelevant outside of Tatarstan and Tuva. They should have equal rights and nothing more.
Tiny countries are often impractical, but small minorities of indigenous people should have way more than equal rights. They need support for their culture, invaluable to humanity, to survive.