Hm. We have a lot of information, but it doesn't mesh well.
An American actor, did movies in the period from 2010 to 2020, but didn't do in the 80s. He appeared in action movies, and at least one major motion picture, but is not well known for comedy. His surname is not longer than 6 letters, and starts with an unvoiced consonant (c, f, h, k, p, q, s, t). And he is not known for being handsome. Not a director either.
It looks like he's relatively young but not known for being handsome. This probably can narrow it down a bit.
We have all this, plus that he's played an antagonistic character in a movie and a single animated character on a non-anime that aired on Adult Swim. And that he doesn't usually have a beard.
By my reckoning, this gives us a really good filter to check any particular target, but no obvious list to trawl through. Movies from 2010-2020 is probably too long, Adult Swim programming is not only long but contains a lot of series with one-off characters that might not even be listed. And if he's only ever played one animated role, it's likely to be something small like that.
So with all that in mind...
Has he acted in a movie released between 2015 and 2020, inclusively?