For years, I played for every Dwarf to survive and thrive. It was great. I liked it.
I've given up and just launch unhappy dwarves into magma. I don't like doing it. I don't like that it's the only thing to do.
I just formed squad on one depressed Dwarf lifted to captain.
Made the squad wear a uniform in foreign clothing unavailable in my fortress like loincloth.
Replace clothing. Exact matches.
At the bottom of my mass-pit I have a 10x9 bridge. Access to this bottom is through 2x1 bridge.
When I spot red arrow it is an instant draft (mostly to captain position through noble screen)
and they go to meeting area, drop all cloths and go to station at the bottom of the mass-pit.
Then I close access. Remove from squad (noble menu usually).
Remove any naming scheme I had on them and like in case game somehow copies settings from dead Dwarves.
Some Dwarf pulls the lever for bottom bridge and problem is over instantly.
No need for magma access or worrying what artisan will do, when his masterworks is destroyed.
Depressing slab at the end, when one week passed. Master quality slabs of course.
This is how I was eliminating vampires in past btw.
Vampires were monsters. Goblins and Trolls were evil. Sick Dwarves are not monsters or evil.
Eugenics sucks, but you can't heal them all from stress with monthly bone bolt crafting
and this game mechanics seems to be very badly designed and is missing a lot in features in implementation.
If Toady insists in keeping psycho mechanics in, then he better spend 6 months writing it fully first (as a full feature like magic).