To save the noobs, the most important thing is to ensure that basic things work in an intuitive way, so the poor new player doesn't spend most of his* time wandering about in confusion, wondering why nothing works despite him having followed basic common sense.
Note also that by asking for money up-front on Steam, you're creating bigger expectations for a bug-free game than for something you're distributing for free with the option of a voluntary donation. So if you want to be in good terms with your new, bigger customer base, I think that bugfixing will need to be done more often and more consistently than once every two years, with basic systems staying broken for 5-10 years.
I think that if you need a wiki early on to figure out which systems are broken and which workarounds you're supposed to apply, you've already lost 75% of regular gamers. Needing one for more complex systems like pumps is probably unavoidable, but by that point at least, if you've managed to keep the player, he's having fun. Or !!Fun!!.
Some notoriously buggy basic things that would need to be fixed, or cut out of the game when non-essential if the fix can't be pulled off in time:
- Dwarves walling themselves off or falling to their death when building or digging. Will randomly kill noobs' favorite dwarves because they aren't paying attention. Requires egregious amounts of micro-management if you want to build something large. -- This is the main reason I don't play DF on a regular basis anymore and stopped donating, BTW, besides my perception of the game losing flavour and challenge since the 2d versions.
- Armor racks and weapon racks (prime candidate for cutting out, if they can't be fixed)
- Bins
- Military equipment
- Suicidal dodging
- Hospitals
- Nest boxes
- Buckets
- Containers in general
- Anything that you notice that people use DFHack routinely for: cleaning, ...
As others have mentioned I also think that the game scales too hard (too many migrants too fast), and too high by default. Designating individual rooms for 7 dwarves is fun. Designing individual rooms for 100 dwarves feels repetitive and a chore - and then you've gotta take care of burying them, too - at which point I expect players who're not motivated enough to use tools like Quickfort to drop out.
It would be nice if you could get all the features of the game at 25 dwarves or something, and if it was the default maximum unless you ask the King for more migrants.
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*use of the masculine to simplify the text while using correct grammar. I'm not implying that girls can't be complete clueless noobs too
.