If that's the bug I'm thinking of we got it too. The water extractors would seemingly change their recipe from water to "Uranium 999" or something and then stop working. We ended up having to build the water extractors on a different body of water to get them to work.
Another bug we encountered had to do with an assembler blueprint I made. I don't know if I overlooked something while making it or if it glitched when saving it, but basically I had two assemblers facing each other belted into a merger that went on to the next merger etc. and there were 8 assemblers total in this blueprint. Somehow one of the mergers got messed up because one of the assemblers just didn't have a belt going into it, but the one opposite did, except the assembler would not output items onto said belt. Disassembling the belt would crash the game. The fix we had to do was delete the merger and the assembler, save the game, disassemble the belt, let the game crash, load the game, then we could disassemble the belt without it crashing so we could actually put everything back together.
We eventually beat the game just by brute forcing machines to build the project parts we needed. Ended up not needing the nuclear reactors. I did build a fuel generator setup that turned 300 crude oil into something like 1,111 rocket fuel, which would have fed about 266 fuel generators. I didn't have nearly enough stuff to make all that but I did end up making about 26 generators which gave him enough power to run one out of six of the machines he wanted to run, so he just did that.