_no_ _walls_
Never ever walls. Unless you have to have them to enclose pastures (so animals do not need to be lead back to them) or around refuse for dead bodies not to be seen constantly on. Just dig/construct huge 56x56 hall like I do. Put 4 3x11 radiating up/down stairs from central 3x3 passage in central corridors. Enjoy your fps improving by 100% the least
_automatic_ _quantum_ _stockpiles_
Mining cart. Construct railstop with auto directional dumping. Learn to use h-hauling routes menu.
_sell_ or _atom smash_
too huge stone stockpiles. Don't let it loiter around.
_z-stockpile_ _mark_ _dump_ _cloths_
All tunics, caps, shoes and mittens. Destroy or sell. Less warn-checks on those. They also conflict with military outfit, so double gain. It will work on owned too. Go every year and dump all cloths from cabinets too, then unmark so these can be used again.
_smooth_ _walls_ _&_ _floors_ _then_ _wall_ _underground_ _digs_ _off_
Smoothing will prevent for vermin generation and walling off will keep animals like cats but not only from pathing into those. Growth & vermin are not your fps friends.
_use_ _pathing_ _value_
Mark low traffic there you don't want your dwarves to go. Mark main roads (like entrance to fortress) with high traffic.
_in_ _init_ _stop_ _filth_ _spread_
_don't_ _keep_ _too_ _many_ _animals_
220 dwarves? 100 animals or less! You won't get enough to leather clothing, but fps will go lighter on you for that. Buy leather for cloths from caravans, if you can.
_don't_ _dig_ _3x3_ _shaft_ _for_ _lava_
Dig 1x1 shaft. When you are done fetching lava, it is easier to wall it off. Mining goes faster. Less stones produced as by products. Easier and faster to wall off any cavern breaches (corners always first. corners will get you!).
_also_
Atom smash non-master quality by products from your legendary skilling. Though sell master quality (if you are not using it), as smashing it is not advised.
_keep_ _stocks_ _small_
if you can. Don't construct when you can dig, as 14k-20k blocks are huge drag on fps, despite existing in constructions. On surface instead of flooring an area you can carve downstairs. Instead of walling, channel a hole and remove ramps from it.