With version 0.1.5, the "Dark Skies" project is finally starting to show some thorns it seems.
In a small world, by the end of worldgen at year 550, the entire eastern half of the map was over-run with what im calling "ghouls".
The total number of Ghouls by year 550 was 3093 with 1874 of them still being "alive". All of this stemmed from merely 3 ghouls all of whom were originally humans, "infected" because they profaned a temple. The "Patient Zero" of the outbreak was a human by the name of Thon Chirpclean, a fishery worker and criminal ringleader, who profaned a temple in a town named "Eyewhipped" in year 84, then proceeded to infect 15 people and kill 24 over the course of the next 198 years before being shot and killed by an elf. The other two outbreaks were uninteresting, each only managing to infect one person.
While the ground zero for the outbreak, "Eyewhipped" became a host to a sizeable ghoul population of 32 ghouls, "living"(more like existing) in the wilderness near the town, the largest concentration of ghouls is way south-east of "Eyewhipped", is around a human town with a population of 2417 named "Ashenbastions", on the same tile exists a lair with ghoul population of 231 ghouls and just about every tile near the town has a lair with at least 10 ghouls. The largest single lair however is just north of "Ashenbastions", near a town with a population of over 2500 humans named "Horsefortune", the lair there has 242 ghouls. Even the elven lands north of "Eyewhipped" weren't doing so well, there was a ghoul lair on just about every tile that the elves own. Dwarves never got off the ground, likely due to the constant conquests by a nearby evil civ, the dwarves only had 3 remaining sites by the end of worldgen. Not even my moon-worshipping lizards were safe from the terror, their sites small and scattered, they had to contend with ghouls in the east, despite being immune to the infection(for now), and Sloghs(giant slug demons) in the west.
The competing ghoul strain(codename "tengu") did not succeed unfortunately, only producing a total of 15 infected, 14 of whom are alive as of year 550. The Patient Zero for this strain was "Pimra Seerbrim", a human scout. Interestingly, Pimra fought with a ghoul and escaped without being infected, 16 years prior to profaning a temple in Horsefortune in the year 201 and unleashing the second strain upon the world.
All this with a background of standard werebeast diseases(and a special, custom one) as well as stuff that is way, way more dangerous in play than in world gen(Boy am i glad breath interactions don't get triggered in worldgen) and I'm far from done with this mod.