Personally what I find most disturbing about climate change are two possibilities:
1) The effectively permanent (on a human timescale) general collapse of biodiversity, as the planet's ecosystems are largely replaced by monocultures (or nothing), and
2) a sudden acceleration of global warming due to the release of methane clathrates, a process that may be unpreventable even if we halt emissions immediately.
One hypothesis that I've heard from a geology professor at my university (take this for what it's worth) regarding the Permian Extinction is that it may have been triggered by a period of intense volcanism (the creation of the siberian traps) which released tremendous amounts of CO2 and other gasses into the atmosphere, which in turn may have raised ocean temperatures enough to suddenly dump most of the methane clathrates that had been accumulating over the eons into the atmosphere. If this hypothesis were correct, then the mirrors to the present day would be obvious, since we have large amounts of methane currently frozen in the oceans and tundras that is right on the cusp of the temperatures needed for release.
Of course, the position of the continents is today much, much different from the time of the Permian Extinction, so it doesn't necessarily follow that total desertification would be a result, and indeed this sort of methane event may have been a recurring event that only triggered a mass extinction under those circumstances, but I think it's totally fallacious to think that the water situation in the event of sharp warming and desertification will be resolved by just moving production around to the "wetter" areas. Moisture isn't what limits production in areas already drenched that may get more intense precipitation, and if anything they may suffer from increased precipitation as these areas are already susceptible to massive flooding. Meanwhile, we can't maintain our current production in the "dryer" areas without depleting aquifers at an unsustainable rate, so further desertification is going to just exacerbate stresses on an already fragile water system in places like the western US and plains.
I'm not terribly worried about food production in particular though, because our current production is so incredibly wasteful. Much of our intensive agriculture goes into producing feed for livestock, something that we could easily tax and regulate out of existence if the food supply were really threatened (leaving meat production to marginal land only suitable for passive grazing, instead of using irrigated fields that employ massive amounts of fertilizer, pesticides, non-renewable aquifer water, etc). Even if we weren't able to improve yields in the future, converting production currently wasted on animal feed and things like corn biofuels could easily accommodate a much larger population than what we have currently. Of course, this sort of a policy-driven shift will never happen in the US, obviously, but the market should eventually drift there if prices on basic staples rise enough (after the aquifers have been depleted, 3/4 of north america is a postcard desert, all those resources on intensive agriculture are wasted, and however much global suffering is endured).
transform the energy market in such a way that the predictions are useless, a-la what happened to Malthus, when nitrogen fertilizers and mechanical cultivation were introduced
I always get triggered when people post Malthus, because the guy was such a goddamn hack. If you read his
Essay on Population (his only work of any consequence, which was in essence plagiarized from an earlier obscure author), the thing is loaded with ridiculous conjectures and inapplicable examples that he just brazenly pulled out of his ass, often without explanation. Malthus' arguments were even for the most part rejected among contemporary economists as being too unsubstantiated (a challenging threshold to pass in economics), and were just kept alive over the decades though his patronage by the English aristocracy who used his statements about the condition of the poor as justification for policies in Ireland and their general position in society. People seem to imply Malthus was correct up until the "green revolution" skewed his "model", but the model was never even in principle near the truth, and doesn't fit
any data sets or time periods!