Not exactly---
Science is about showing what is not true, rather than what is true. It's about falsification.
For example, one can demonstrate the falsity of the claim that the earth is flat, using simple trigonometry with noon-time shadows at different longitudes. (The Greeks figured this out thousands of years ago.) This does not prove that the earth is spherical; More modern measurements show that it
is somewhat lumpy, rather than actually "round". Such measurements demonstrate the falsity of claiming roundness.
Likewise, we have progressions in quality of predictions using mathematical models of physical processes. Notable examples are classic Newtonian physics, vs Einsteinian relativity vs Quantum physics. Each is a step that falsifies some of the features of its predecessors, and produces a superior (better represents direct observation) model of the universe's mechanics. At some point, we will "Actually have a genuine understanding", at which point revision of the model will not be possible. There are some people that think this might be happening with particle physics, since the standard model has held resolute for so long, and more exotic models have not had the same success at predictions that SM has had, even though "there are strange things happening at the circle K", like dark energy, dark matter, and pals, which hint at broken symmetries and other interesting physics just around the corner.
The process is all about elimination of what can be proven to be false, eventually leaving either only that which is true, or that which is inscrutably ambiguous. (and yes, some things are fundamentally unknowable. For instance, knowing both the vector of movement and the position of a quantum particle.)
Either way, there is methodology and data that exists OUTSIDE of the human mind or its symbols, which demonstrate the falsity of human derived symbolic representations of reality. (EG, actual reality, vs perceived reality.)
The refusal of those methods and that data, in favor of the internally produced symbolic representation is the fundamental issue here. It is a refusal of accepting a truly shared external, and uncaring reality as the true existence outside of our personal experiences, and the preferential clinging to the models our minds have created instead, regardless of their demonstrable falseness.