Right now the main priority is getting nail+tool production going. You can just buy iron ore on the market and smelt it in your hamlet, then make a forge and train a toolmaker. That is the base of all right now, because trying to buy these things on the market is a terrible idea (people like me are scalping all the tool prices to stupidly high prices.)
Once you have nails and tools, you probably should focus on building material production. Wood+Stone, and whatever other minerals you can find. Gold, gems, copper, etc.
Also, the new version means you need to cluster pretty hard. That means putting the bulk of your domains right on top of each other and connecting with roads. This allows goods to flow between them automatically. The main thing here is to connect a village with a town. Village extracts resources, town refines them. Then a lordship for the military. So a triangle of village->town->lordship is a solid start. If you're solo, aim for a city and then more lordships probably. I'm not exactly up-to-date on all this, since I did not play in LoL5 or LoL6.
If your starting hamlet isn't a good spot, then definitely focus it on producing whatever you can to bootstrap your next domains where you want them.
The big factions have pretty much already chosen their main areas to focus in. I'd recommend Samotras and joining me, and the archeotype crowd :joy:
P.S. I forgot to add: always make your next domain after the 24hr timer is up asap. Even if you don't need the space, you can take those three free workers to your main domain (as long as you have the same lord for both places) and use them as cheap labor to build faster. Just bootstrap speedup tip.