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[em1LL]

Will blood in a water source attached to a well result in an infection of wounded dwarves?

If so, will pumps clean it?

[PatrikLundell]

No.
A vampire fortress is generally created by getting a "source" vampire to bleed in the well, but it's apparently rather hard to get it done correctly, as the blood has to be directly on the tile the water is drawn from. No other blood infects, although I wouldn't be totally surprised of blood contaminated water would act somewhat like muddy water (i.e. not as good for cleaning as clean water). However, blood contamination would only be an issue if the blood is directly in the tile the water is drawn from, not further up the chain.

[King Kitteh]

Pretty sure that pumps clean anything from water.

They even remove salt!

[ragincajun]

ooh, I'll have to watch for this.  I was recently attacked by a werecreature who got in through a "root hole" early on.  He killed two dwarves before reverting to human form.  I was digging a pit shortly thereafter for breaching the magma and when they began putting water in it I noticed it was red and had some of his (the were-human) blood in the water.  It did clear up from red to blue on it's own and the blood reference disappeared (no water wheels or anything else) and don't believe anyone used it for a drinking source (2/7 level).

[Fleeting Frames]

While vampirism does transit through a well of blood, the complicated, high mortality setups to give lycantrophy to milita suggests that werebeast blood is non-infectious.