Well, one lunar outposts produces .035 unobtainium per second. So if you can keep it fueled, that's 5000 in 39 hours. Build 4 and it's 10 hours. But yeah, you're going to need planet crackers to trade with leviathans. 1 planet cracker generates as much uranium as 120 accelerators.
This is only true without magneto's and steamworks. Magneto's increase accelerator output but not planet crackers. By increasing the magneto multiplier and building accelerators you can get enough uranium to run a lunar outpost even before getting the cracker.
But, you need tons of blueprints for the magneto and steamworks. (Though, I personally tend not to craft blueprints.... got a nice stockpile of compendiums.)
Maxing accelerators probably could be done for the storage capacity anyways, but I don't know how much that is needed in a you got a lot of paragon run.
Also, after 3 thousand years, starcharts are totally not a bottleneck for a non-reset kitty civilization. (Over 45k stockpiled after the fracking and uranium planet.)
Bottlenecks in non-reset:
Plate/Iron - when trying to up harbor capacity. Probably other stuff, too, but that is what sticks out. Stops being a huge problem after that, cause steamworks.
Steel - All the damn time. Just keep on stockpiling that as soon as you have access to coal. That calcinator thing does not add up to the quantities you actually need.
Titanium - When first introduced.... then it ain't really a problem once you can make your own. Trade is pretty awesome for closing the gap, especially when you have over 2000 ships. (Heck, I'm swimming in titanium. Most things that require titanium, other then the steel/oil/blueprint ones have already been maxed to capacity.)
Oil - Huge problem at first is capacity, to get into space. Then you need tons more in the form of kerosene.
Uranium/Unobtanium - Basically the same story as Titanium...
Science - Capacity becomes a problem around when you hit the space age... buy compendiums.
As for Factories... since its a non-reset... you are in for the very long haul. Max that thing.
Don't skimp on the Slab production. Concrete brutally murders the stockpile, like how Alloy graphically dismembers the stockpile of Steel...