Not gonna spoil anything (just hint at things, though there might be some, but unless your internet was off or you didn't look at the features, you'll know the features anyway)
But after playing both a female and a male, I doubt I'll ever play a female in this game. I don't enjoy my female character at all. usually (not always) i go with a female character in games (didn't like males at all in skyrim, nor fallout 3 or new vegas), depending on what genre of game, races and how the males look, amongst factors. But in this case, the female doesn't really fit the pacing and world that bethesda made because of her backstory.
the male however fits so much better. The females previous job wasn't a combat job at all, it wasn't even leading people, and in the game you suddenly go to building a settlement (which doesn't fit her at all)
the male's previous job however fits perfectly. I mean, his current job in present times (in the game) isn't really very different from what he was doing before. It makes sense for him to suddenly go in and start ramboing it up against raiders (not so much the female) and I can see him building a safe haven as well.
The female, its way too jarring playing as one. A backstory of no attacking or anything, suddenly going into power armor, big guns...building a settlement...fits so much more with the male due to his backstory before the bombs fell.
after going back to my male character, I'm enjoying the game a lot more ;P Even if its just a backstory and doesn't really effect the game, its still part of it and kind of very jarring knowing what it is and knowing everything I was doing on the female didn't fit her at all.