Got an idea for an X-files adjacent kind of game. Set in the modern period, sometime in between 1920-1970 or so.
The PCs would be agents working for a Men in Black type secret organisation, working to suppress knowledge of various supernatural or supernatural-adjacent phenomena and threats. Werewolves, zombie viruses, vampires, wendigos, cryptids in general, that sort of thing.
The organisation started out as several groups of knights, monks, priests, doctors and so forth from around the world who had taken up the cause of hunting their local 'monsters' to protect their own people, but after efforts to utilise these monsters in one or the other World War* it was decided that the various groups of monster hunters needed to come together and cooperate to prevent the threats they had been guarding against from being released upon people en masse by malevolent actors, and most of these groups have come together to form a unified clandestine body which operates semi-independantly from the nations of the world.
Now the main two threats the organisation deals with are wild outbreaks of the things they seek to contain, a werewolf preying on the people of an isolated region, a town being laid siege by undead after it's water supply became contaminated with the zombie plague, and the human radicals who seek to weaponise or irresponsibly study the pathogens, species and stange forces behind these events.
*Perhaps Nazi Werewolves, or British Zombies. Whatever plan, it would have been nipped in the bud.