Ran my first real-life, in-person, flesh-and-blood pen-and-paper RPG session a few days ago, start of a Mutants and Masterminds campaign for my friends. It was a ton of fun - we ended up playing for almost ten hours because no-one felt any need to stop. The basic gist of the story was: star professor of an MIT-knockoff university has been manipulating his star pupils and using them for a string of crimes, proper criminal mastermind-style. Heavily investigation-based, but with enough scraps to make things dangerous/interesting/varied.
That's not to say it went perfectly; I had trouble getting a few players involved at the start, because they felt their characters wouldn't have any reason to involve themselves in the power-armoured bank robbery I had there to start things off. It worked out in the end, but they just sat there for a while. I also didn't get to show much characterization for most of the bad guys, though some NPCs that weren't even supposed to feature heavily did end up getting the spotlight. But hey, that's the way it goes, no problem there.
Also, though I prepared for the mind controller and prepared for the superspeedster, I sure didn't prepare for them working together in a situation I'd just improvised into existence. I put one of the villain's minions to shadow them without really considering how he'd get away if they went after him. They caught and mind controlled him, and it ended up being somewhat of a farce of a scene for a while as I furiously thought of some way to not have them spoil the entire plot at that point.
Eventually one of his accomplices sent his drones in, which actually managed to incapacitate the (incredibly squishy) mind controller and let the dude escape. They got a fair amount of information out of him, which was good for the story, but he did manage to get away, which was even better for the story.
Still, for the vast majority it went great - the players followed the plot much better than I'd actually expected, though there was a few times where they weren't totally sure of what to do. The best bit was probably an interrogation of one of the students that devolved into dark comedy as the Constantine-style mage accidentally almost killed her, leading them to lock the Director of the university out of the room and then create an illusion of everything being totally fine when she finally got in. They also had an unexpected amount of trouble with a seemingly unkillable student with power fists who kept rolling really well, all the time. Who they also decided had a choking fetish after he got force choked by the group telekinetic. I never thought I'd get to roll Insight for discovering new fetishes.
The main villain got burned and crippled at the end, and is definitely coming back... as Crucible, evil mastermind of super-engineering! His minions will also probably return, at least the memorable power fist dude. At some point, anyway.
Any tips or comments for a GM who's mostly run things online and mostly on forums before? I'm having a ton of fun with all this.