Organ cloning is something that already exists and is used extensively. As well, small genetic alterations to repair genetic defects and diseases work without any apparent unforeseen consequences. However, to do these on more than an ad-hoc basis with whatever medical facilities you bring, you'll need a dedicated cloning kit like the Meat-Vat kit(which can be repurposed to some extent) or the LSL
Immortality here we come!
According to
Moore's Law, transistor count doubles twice about every 2 years. Now I'm not very smart when it comes to IT but I think that means that if the standard storage of a computer is 1TB, then it 2 years the standard amount will be 2TB. Now, assuming that today's standard is 250GB (it's actually closer to 500GB or 1TB, but let's low-ball it), the average storage of a computer is 262TB after 40 years time. That should be enough storage for plenty of movies, books, games, etc. on each personal computer, no?
What I'm saying is that the tech needed to keep someone occupied for 15 years in deep space would be available on the equivalent of an iPad, especially if we include some impressive iterations of the Oculus Rift. Again, why spend so many resources on large, space-taking VR pods when we can get the equivalent in someone's backpack?
EDIT: What's A.I like? Is it human-like yet? It would be wise to know before we jump on board with a potential HAL 9000.