Here's what I do for weapons, since people are complaining about those:
Make things interesting, or RP if you want. Let's say you're a Glitch Peasant, for example. Let's also assume you're afraid of whips, and don't know how to use any type of gun. That limits you to melee weapons, and a few things, like boomerangs or chakrams. Or, pretend you're a novakid cowboy, and only use duel-wielded pistols. That limits you a lot on what you can use, but it also means you can still craft weapons if you need.
As a side note, all bosses drop weapons. All of them. My favorite is the one from the Hylotl quest, because it's a pretty awesome katana. Sure, there's some better weapons in the game, but it's cool to have a sword that lights up when you swing it and lets you throw kunai.
Oh, and if you're looking for something specific, go
Here. While it's not %100 accurate, it's pretty good.
Honestly though, to me this isn't a game to be played alone. Yeah, it can be fun every now and then, being the sole explorer, discovering the hidden treasures of the universe. But it's so much better with friends. You can do missions together, explore, be a squad of penguins with rainbow swords that cut holes in the universe, build a civilization spanning a world, or whatever else you can imagine, and it's just so much better when your friends are there to help you do it. Because, if you think about it, isn't that why we have a forum? To talk to our friends about things that interest us? Don't we already play games together, this one's just a bit more fast-paced than most?