That depends on if they're normal swords or someone made a necromantic sword of death touch yet. And I highly doubt your giants are as hard to kill or have the regeneration factor of the titans...
They're big, but that doesn't keep a group who knows what they are doing from winning.
(Or an Illusionist swings by and exploits their need for orders by giving them the illusion of not hearing anything.)
I don't think any of the current gods are even capable of creating necromantic swords, save Joha, but it would take her a lot more Essence than it would a god of death. Humanos Grande are easier to kill than titans and have a healing factor equivalent to humans.
A group would probably win against a Humanos. I'm talking about a one-on-one fight.
The Humanos are actually half-sentient. They don't
need to be told to do something to do something so if they get attacked they WILL fight back, but their free will can be instantly overriden by an angel of Yaos. If the illusionist cuts off their hearing, they won't be able to get ordered around by angels but they'll still fight back against the person or people trying to harm them. Oh and the Controller Angels can tell them what to do psionically. It's the most efficient way to control a hundred Humanos Grande at the same time, after all.
Or a bird person drops rocks on them from above.
There are lots of ways to beat one, big doesn't mean unbeatable.
They are not unbeatable. They are very beatable. But there are no giant rock-dropping birds in the world so they are top food chain.
Or, all the things the Gruen have access to:
1. An Archangel
2. Poisson
3. The fact you need a human to pilot them
4. Camouflage
5. Divine intervention
6. Starvation (The god of hunger IS your enemy, and those things take a lot to feed)
6 ways off of the top of my head.
Things that humans have access to:
1. The Angel-Emperor of Mankind (an archangel) with a fire sword made by the god of weapons himself
2. Flamethrowers
3. 1,000 Humanos Grande that don't need pilots
4. More flamethrowers (and Humanos-sized grenades)
5. Divine intervention
6. HUMANOS GRANDE AND ANGELS DON'T NEED FOOD, SILLY N'WAH. THEY ARE SOLAR-POWERED AND IMMORTAL, RESPECTIVELY.
2. Poisson
Do not question the power of Summoning Bigger Fish!
Indeed. See: Aev'a
I will say now that there are TWO ways to kill a Humanos Grande. Decapitation is NOT one of them.
Technically. It certainly does help with one of the methods.