Personal favorites:
Red Moon Rising"Red Moon Rising is a full-colour steampunk fantasy webcomic set in the midst of a magic-fuelled industrial society, following one person’s mistake and the knock-on effect it has on the people and the world around them."
Everblue"In a world of endless ocean, a young shipwright named Luna meets an odd and cheerful drifter when he crashes his flying boat on her city's dock. When strange circumstances force Luna to leave her home, her once quiet life quickly takes a turn for the unpredictable. In an instant she is swept up in an adventure that will take her beyond the bounds of the charted world and into the Everblue, following the path of an ancient legend with the potential to change the world forever."
Ava's DemonA very pretty comic about a girl haunted by a demon in a sci-fi universe.
String TheoryCouldn't really figure out a good description, but it's really good. Read it.
Namesake"Namesake is the story of Emma Crewe, a woman who discovers she can visit other worlds. She finds out that these are places she already knows – fantasy and fairy lands made famous through the spoken word, literature and cinema. Her power as a Namesake forces her to act as a protagonist in these familiar stories as she figures out how to get home."
Dead WinterWanna-be poet formerly waitress tries to survive the zombie apocalypse.
LackadaisyProhibition-era St. Louis, with CATS! And GUNS! And SPEAKEASIES!
Unsounded"Some dead men tell tales, and some little girls have tails...
Daughter of the Lord of Thieves, Sette Frummagem is on a mission, and she'll lie, cheat, and steal to make sure it's a success (she'll lie, cheat, and steal anyway). Condemned to aid her in her rotten endeavours is a rotten corpse who seems oddly talented with the supernatural, and oddly not laying motionless in the dirt.
The road is long and no one is what they seem. Never trust a thief, and never trust anyone who won't let you look into their eyes."
Girl GeniusWonderfully mad science!