I like
XKCD
SMBC
Dr McNinja
Bravemule
Cat and Girl
Sinfest
Gunnerkrigg Court
Erfworld (stopped reading when they switched to alternating one comic with one stupid wall of text)
Subnormality (may be on hiatus, haven't checked in some time)
Nodwick (D&D comic generally superior to Order of the Stick, which I felt was kind of garbage. I mean, the guy who draws Marmaduke hasn't improved his art over the years either so I guess Rich Burlew is fine right?)
Axe Cop (dunno if still running, haven't checked in some time)
Penny Arcade / Trenches / Camp Weedonwantcha
Three Panel Soul (and I used to read Mac Hall when it was still running)
Goblins (although I guess that's on hiatus)
Copper (hiatus)
Perry Bible Fellowship (I guess hiatus?)
VG Cats (hiatus)
Achewood (semi-hiatus, possibly just recovered from hiatus and may die again at any moment)
Oglaf (NSFW)
8-Bit Theater was fine. I wouldn't re-read though.
Probably a bunch of others that I'm forgetting. I tend to stop checking if they stop updating, and then discover the comic again and read through the updates. Like I'm about to do with Axe Cop and TPS.
Oh man and I used to ready Wormy in Dragon magazine and I was soo sad when it ended. His art was beautiful. I just really like anything Dave Trampier drew. He burned out I guess and stopped making art and became a cabbie somewhere.
Also enjoyed Yamara, although I was too late to catch Fineous Fingers.
Uh oh. I never thought of myself as someone who reads comics. EXISTENTIAL CRISIS RISING