I find it in fact easier. With the many starting points and the easiness of farming, food is now a complete non-issue, as is booze.
With the new terrain (which i absolutely love, every map is different) you can't use the same strategy over and over again. (Which is a good thing imho, the old version did start to repeat itself after a few tries, which isn't good for a procedurally generated gameworld like in df)
Balancing is way off, but this is to be excepted for an alpha, after all. DF isn't a game where you get the "highscore". I see it as sandbox-game... a software toy if you will. The goal is playing, do as you wish.
I first thought the z-axis will make the game totally indecipherable, well I think I was wrong. It in fact comes naturally and I can't even think about playing df without a z-axis anymore.
The interface is the interface, I don't even find it as terrible as many people think here. There was a time where every single Interface of every strategy- or RPG-game looked like that. Many of this games where completely unplayable without manual. DF isn't even one of this games, you can learn to play it without manual. Much things in the gameworld are quite logical and toady did a good job to remove some of the things wich make the previous version tedious and cumbersome at some point in the later game.
Long post... all in all, I find the game easier.