Space is a pretty good insulator but starship is not, as evident by the condensation and ice patches forming immediately upon prop load,
Starship has good enough insulation for the purpose; remember that that is formed in
air which conducts heat a lot more readily than
vacuum and it's due to the substantial time it takes to load the Starship, which lets the whole thing cool down dramatically. Once in space, that stainless steel hull will reflect most of the sunlight striking it, while on the dark side the temperature in earth orbit is like 20 Kelvin or something like that? It's not quite the universal background 3 K but it's close.
In short, the actual rocket scientists who set this up do in fact know what they're on about. They won't lose all their propellants no matter how long the mission goes.
Autogenous pressurization is just "use the propellant to pressurize the propellant tanks" but IIRC the precise way SpaceX is doing it relies on the exhaust from their gas generators, which is a great place to get hot gas to pressurize the propellant tanks, which does bring along some CO2 and H2O because those are the products of the reaction. I could be wrong there, I'd have to go back to whatever EverydayAstronaut or Scott Manley video mentioned it.
The reaction control/attitude control (same thing) thrusters use the gaseous component of the tanks, but as far as I have heard the larger methalox thrusters that are going to use the liquid component to aid in thrust, because even in 1/6 gravity you do still need a good amount of force to land the 120+ ton (depends on how much fuel it's burned at this point) Starship on the lunar surface.