In any situation where we say "I bet we could send some of Earth's extremophiles to that other environment, and see if it can adapt to it" is, by definition, a place where Life As We Know It might already be found if we look hard enough. If it isn't independently arisen (maybe not predominantly in the Earth-Extreme places that we imagine it be, but in other places that might be harder to check but adjacent to them) then perhaps it has been already sent there via the extreme measure of hitching a ride on interplanetarily-transferrred impact debris (a provable thing, and may have happened a lot so the dice have been rolled plemty of times for at least one successful hitchhike ride and arrival).
Inoculating a 'dead' world could be deemed an attack, philosophically. The saving grace being that surely any 'native' organisms will by now have become better at dealing with local extremes than our kludged-together (or manually re-designed) seeding ones could ever be, this side of the biogenomic mastery needed to become the Progenitor race for some future's weirdly coherent galaxy-wide Panspermia origins.
Still, it messes things up. And as there doubtless is Life, But Not As We Know It (in as yet unknowable ways until we find at least one of the 'other answers' to The Meaning Of Life), at some point a messily incomplete survey that reveals no DNA/etc but overlooks <insert currently unknown alternative here> is going to allow us to do something we might regret later.
(Current biosecurity efforts might have already insufficiently sterilised our interplanetary probes. It is not even beyond contemplationnthat our attempts to avoid contaminating the moons of Jupiter/Saturn by sending our probes into the Jovian/Cronian atmospheres could have actually inadvertently sent a declaration of war against the respective Blimp-Creature civilisations therein! Yeah, protect the theoretical liquid-water life, but feel free to discriminate against the more dissimilar forms of life-organised matter! And these are beings who might, othewise, even be valuable allies in the future war against the coronal magnetodynamic beings who some day will organise deadly solar flares directly, deliberately and continually against us because of some other perceived slight or (on their part) rampantly nihilistic xenophobia! At least until the next bigger threat, like the Black-Hole Flingers/etc.)