But then, why launch from the Moon instead of constructing your sci-fi scale interplanetary ships in orbital space directly? On the Moon, you're still sitting at the bottom of a significant gravity well, but you don't have enough gravity to actually ensure the health of your local workers without additional measures. You don't have the mineral resources of Earth, and you can't tap a convenient NEO that may have the heavy elements you need in abundant supply much more easily on the Moon than you could on Earth. You also get to worry about that lovely sharp lunar dust getting into everything; your entire construction area needs to be safed against it unless you want to worry about damaged gaskets, sealing, wires, fine lenses, and so forth.
EDIT:
Ah, at any rate, my own thoughts. I see the moon being primarily a resource-extraction industry at the very most, albeit one primarily focused on relatively light elements: helium-3, oxygen, water, and (on the heavier side) aluminum and maybe iron. It's generally believed that short of a trip out to the outer planets, the Moon is the most convenient source of helium-3 in the inner system. This, however, requires effective cold-fusion to make any use of 3He; most present uses for the isotope aren't really worth the cost of going to the Moon and back. Even as a power source, it's questionable if it's worth the cost. A space economy is likely going to be centralized in Earth orbit with possible occasional forays to near-Earth objects or even the asteroid belt for the foreseeable future. While resource extraction is going to be major due to the wealth of accessible resources available in certain types of asteroids, zero-G manufacturing does have significant promise. Power generation is also a possibility: without gravity, tremendous solar arrays can be constructed without the structural support necessary on Earth, and without occlusion by weather or the planet itself, can operate continuously, but the question then becomes if efficiency losses from power transmission from orbit to the ground outweigh this.