Had quite a fun excursion just now.
So my little colony of five (three original settlers plus two acquisitions) got a little stabilized, and I decided I could start acting on the various quest markers.
The game helpfully tosses me a ridiculously useful quest - an item stash of just one item. A resurrector mech-serum. Guarded by just three people.
What the hell, sure I'll go.
Three steps out the colony, the first attempt is aborted because two of the three caravaneers contract malaria and the plague.
At the same time. Tropical jungle, yay. The game clearly wants to tell me something.
While the away-team-to-be is recovering, a new quest pops up in the same direction. Adam, the lover of Holloway (one of my original three), is incapacitated and stuck in a bandit camp. Two bandits, two turrets, and a mortar somewhere in the middle of a nearby swamp, just past the item stash.
Okay then.
Away team - three people and one elephant - is reassembled and aways without further issues. The item stash is reached easily. Us, three people with guns, and the bandits, three people with knives and a bow, have a short discussion about who owns the valuable item in the shack over there. The lone escaping survivor agrees with our point of view, and the caravan packs up with the mech-serum and a couple useful trinkets like standing lamps and an excellent steel bed stowed safely on the elephant.
The trek through the swamp from the stash to the rescue site takes longer than the trip from the colony to the stash, but I figure we have about enough food for the trip back as it is. Then, a few hours before the caravan hits the rescue site, Holloway contracts muscle parasites. Her rifleman skills become immediately less useful, but no turning back now. The site is reached, and wow how is this a swamp and not a forest. Trees bloody everywhere.
Now, this would be my first time actually engaging a mortar emplacement, but I sort of got the gist of how it works. Problem is nobody can get close because there's a turret in the way. Holloway with the rifle sets out to shoot out the battery that connects the turret to the rest of the power grid, while 'All-Trades' the reliable handywoman with the SMG, shoots the bandit not operating the mortar. 'Savvie', the shotgun-wielding commissar in marine armor, makes a beeline for the mortar itself through the swamp and the trees.
All-Trades successfully kills the second raider, while the first mortar shell nearly takes off Savvie's foot (and many other organs, but armor protected those, presumably). Holloway eventually takes out the turret's battery, and narrowly dodges the second shell that badly injures All-Trades. All-Trades starts bandaging herself while Holloway and Savvie charge the undefended mortar. Before the operator is killed, he manages to fire two more shells. One misses Savvie as she makes it into minimal range and starts putting fist-sized holes in the raider's limbs. And then Holloway also moves in closer to get a better shot, which leaves All-Trades as the only target in the mortar's effective range.
Welp.
A short deliberation later, the mech-serum is used on All-Trades because a good colonist is a better use of it than... well, not using it. But now she's got resurrection sickness, and Adam, the rescued lover of Holloway, is in fairly terrible shape. And the caravan isn't well stocked enough on food to stay here for however long it takes everybody to recover, or trek back with two disabled people and a loot-loaded elephant through the tropical swamp.
A small hospital is erected out of disassembled surroundings and the caravan's sleeping bags, rhinos are hunted for food, and a couple days later All-Trades is back on her feet and I'm considering just moving out as-is because it's clear that Adam isn't recovering anytime soo... and now Adam is dead. What?
Brain damage. From go-juice withdrawal. Oh so that's why he wasn't recovering. Welp. No reason to stay anymore.
Holloway is obviously distraught, but is bizarrely held up by the lingering positive thought of 'rescuing' Adam. Well let's not waste time, then, everybody's spirits are low enough as it is. On the way back, Holloway has a minor break and then contracts the flu.
And thus the expedition made its eventual return to the colony.
They didn't bring back the mech-serum. They technically didn't rescue Adam - though what remains of his body after a week of trudging through the tropics stuffed into a saddlebag, is now interred into a nice slate sarcophagus in a cave next to the main colony buildings. Holloway is barely stable, and is going to be crashing into break territory in a day or so as the lingering positive thought disappears. She is also still infected with muscle parasites. Also wasted a whole lot of time, almost had the main colony burn down because of too few people to fight the massive forest fire, and had a significant amount of vegetables that didn't fit into the freezer rot away in the stockpiles.
But also brought back a couple mini-turrets and a mortar, so I'm filing it under "technical success".