Some gargoyles appeared during a booze shortage where my dwarves had to DRINK FROM THE RIVER like filthy ELVES or HUMANS. I lost about 5 random, generic dwarves I don't really care about. This happens every god damn time gargoyles appear.
Also, somehow, one of my dwarves caught the black death. By the time I realized what was going on, it was too late. Too many people were infected. I tried to make medicine to combat it, but nothing seemed to work. There were tantrum spirals, rabies, berserk dwarves, death, and chaos. I had no choice but to abandon the fort.
Started a new world with a new fort, "Oh hey pal, how about some free influenza to start off your embark? You know, for FUN?"
This shit is why I'm turning off diseases.