We still have some physical evolving to do. Our primary assets are our intelligence, our extruded substances, and our ability to exploit (whether symbiotically or parasitically) other species and other members of our own. I say we improve on their potential, before we shift our evolution to mainly social, cultural, and technological modes.
Extend maximum lifespan. We no longer benefit from short generations if we don't mutate much. Longer individual lives may allow for living archives of memory, and produce experts in given tasks due to long periods of focus, helping with specialization and training through apprenticeships.
Introduce (mild) tendency toward insanity. We mustn't become stagnant. A few individuals each generation that ignore the rules and do things their own way can be sources of surprise innovation. We need our Nikola Teslas and other mad geniuses. Essentially I'm suggesting we build in a way for the GM to give us boosts and new stuff via random chance, not simply near-extinction events.
Improve memory. All our advances and experiences mean nothing if we can't keep track and have to keep re-discovering them.
Improve electrosense range, precision and emission. We don't have magic, but we can have radio-telepathy, albeit maybe not in that particular section of the electromagnetic spectrum. This can also be useful to control newly developed/encountered creatures via implants, when we get that far with our technology.
Gain ability to refine and incorporate non-food ingested materials into our webbing and venom. We're almost certainly going to have medicine and materials science. Being able to use our own bodies to produce some of it will give us an edge.
Gain ability to incorporate viral DNA into our own genetic structure. Continuing our fine heritage of using or absorbing every useful non-us thing that comes along. No, I'm not talking
Resident Evil, though that'll be amusing when it inevitably happens. I mean more
along these lines.