So when is a geographical area considered too small for self determination? Scotland? Inverness? Dunbarton? Farmer Jim, his wife, two sons, and dog?
Anything within reason, to be honest. Individual human beings already have some kind of "self determination" outlined under the declaration of human rights. If there was a movement calling for Inverness to be independent I wouldn't oppose it. Thing is though - there is no such movement. Right now, we're talking about Scotland - generally regarded as a nation that is going to have a referendum.
So you'd oppose greater European integration then. Also, I don't see why the "UK" level of government would be less legitimate that a "Scot" level of government. After all, Edinburgh for exemple would still not elect "its" parliament, having its wishes trumped by that down "rest-of-scotland" imperialists.
I would oppose European federalism, yes. Not necessarily a European Union that doesn't govern the macro-economic policies of the Mitgliedstaaten or their foreign policies. I have already explained though that, in my vision of an independent Scotland at least, we should have devolution within Scotland to give regions like Edinburgh (the Lothians) regional autonomy. Scotland is in danger of becoming a very centralised state post independence, although it wouldn't be any worse than it is now to be honest.
I'm just going by the precedent here - we're discussing Scotland's independence, Scottish rights to self determination and so on. You can do that whole "slippery slope" fallacy thing all you want but it doesn't really change things.